Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427394 | 0.90 | NR1H2 (0.51) | NR1H2NR1H3FAAHPPARGPPARA | |
| SCHEMBL6426743 | 0.87 | CMA1 (0.57) | NR1H2NR1H3ALDH1A1LMNAPPARG | |
| SCHEMBL6427927 | 0.83 | MAPT (0.52) | NR1H2NR1H3ALDH1A1LMNAPPARG | |
| SCHEMBL6427000 | 0.81 | NR1H2 (0.60) | NR1H2NR1H3ALDH1A1FAAHLMNA | |
| SCHEMBL6428843 | 0.79 | NR1H2 (0.52) | NR1H2NR1H3ALDH1A1FAAHLMNA | |
| SCHEMBL15923547 | 0.76 | KMT2A (0.60) | ALDH1A1FAAHLMNAKDM4ETDP1 | |
| SCHEMBL6428883 | 0.76 | NR1H2 (0.48) | NR1H2NR1H3ALDH1A1LMNAKDM4E | |
| SCHEMBL6427259 | 0.76 | ADRA1D (0.49) | NR1H2NR1H3ALDH1A1KDM4ETDP1 | |
| SCHEMBL6426484 | 0.76 | APAF1 (0.52) | NR1H2NR1H3ALDH1A1TDP1MEN1 | |
| SCHEMBL6429547 | 0.75 | CMA1 (0.54) | NR1H2NR1H3ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005024755-A2 | MEDICAMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS OR DIABETES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2005-03-17 | — | — | WO | disclosed |