Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 12/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843098 | 0.80 | CRHR1 (0.43) | — | |
| SCHEMBL8344779 | 0.79 | CRHR1 (0.47) | — | |
| SCHEMBL6428203 | 0.78 | HPGD (0.33) | SCN9ASCN5A | |
| SCHEMBL6428379 | 0.76 | CRHR1 (0.42) | — | |
| SCHEMBL5844636 | 0.72 | CRHR1 (0.43) | — | |
| SCHEMBL6796988 | 0.71 | PLA2G2A (0.37) | — | |
| SCHEMBL6429709 | 0.71 | PDE4B (0.36) | SCN9ASCN5A | |
| SCHEMBL6803037 | 0.69 | PLA2G2A (0.34) | — | |
| SCHEMBL5843407 | 0.69 | CRHR1 (0.42) | — | |
| SCHEMBL5844156 | 0.69 | CRHR1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |