Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428379 | 0.95 | CRHR1 (0.42) | CRHR1NR3C1NR3C2 | |
| SCHEMBL6428206 | 0.79 | SCN9A (0.35) | — | |
| SCHEMBL5599406 | 0.77 | CRHR1 (0.69) | CRHR1 | |
| SCHEMBL8344776 | 0.75 | CRHR1 (0.40) | CRHR1NR3C1NR3C2ALDH1A1PGR | |
| SCHEMBL6430833 | 0.74 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL6393222 | 0.73 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL5843235 | 0.73 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL5843230 | 0.73 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL6428374 | 0.72 | CRHR1 (0.38) | CRHR1ALDH1A1 | |
| SCHEMBL6428447 | 0.72 | CRHR1 (0.52) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962479-A | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 1999-10-05 | — | — | US | disclosed |