Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844014 | 0.63 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL31280713 | 0.62 | KDM4E (0.38) | — | |
| SCHEMBL6446320 | 0.62 | CRHR1 (0.47) | MEN1KMT2ACRHR1 | |
| SCHEMBL13677216 | 0.62 | FFAR1 (0.44) | HPGDNPSR1 | |
| SCHEMBL8993442 | 0.62 | MEN1 (0.53) | MEN1HPGDKMT2AALDH1A1NPSR1 | |
| SCHEMBL5844373 | 0.61 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL5846010 | 0.61 | CRHR1 (0.78) | CRHR1 | |
| Propane SCHEMBL28061941 | 0.60 | TSHR (0.58) | MEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL5843396 | 0.59 | CRHR1 (0.39) | CRHR1 | |
| Ether SCHEMBL7455606 | 0.59 | TSHR (0.52) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |