Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845385 | 0.70 | HPGD (0.32) | LMNAKDM4E | |
| SCHEMBL8806288 | 0.67 | NOS3 (0.36) | MAPTGAALMNAKDM4ECRHR1 | |
| SCHEMBL3807690 | 0.65 | HPGD (0.44) | GAAKDM4E | |
| SCHEMBL8341776 | 0.64 | CRHR1 (0.36) | KDM4ECRHR1KMT2A | |
| SCHEMBL5843759 | 0.63 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL6428640 | 0.63 | MAPT (0.35) | MAPTL3MBTL1LMNAKDM4ECRHR1 | |
| SCHEMBL5844075 | 0.63 | CRHR1 (0.46) | MAPTL3MBTL1CRHR1 | |
| SCHEMBL12772147 | 0.62 | MAPT (0.53) | MAPTL3MBTL1GAALMNAKDM4E | |
| SCHEMBL22912563 | 0.62 | MAOA (0.32) | LMNA | |
| SCHEMBL5867095 | 0.62 | DRD1 (0.48) | GAACRHR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |