Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 11/20 | 0.53 |
| ▸ | GSK3B | P49841 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426953 | 0.74 | GSK3A (0.41) | GSK3AGSK3BALDH1A1NPC1RAB9A | |
| SCHEMBL6428260 | 0.71 | GSK3B (0.80) | GSK3AGSK3BCCNB2CDK1CCNB1 | |
| SCHEMBL3384007 | 0.70 | GSK3B (1.00) | GSK3AGSK3BCCNB2CDK1CCNB1 | |
| SCHEMBL6032840 | 0.65 | CHRNA7 (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2NOTUM | |
| SCHEMBL6427982 | 0.63 | GSK3A (0.69) | GSK3AGSK3BCCNB2CDK1CCNB1 | |
| SCHEMBL354607 | 0.63 | RAB9A (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2NOTUM | |
| SCHEMBL2737273 | 0.62 | RAB9A (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2NOTUM | |
| SCHEMBL7221639 | 0.62 | RAB9A (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2NOTUM | |
| SCHEMBL13876157 | 0.62 | SLC6A2 (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2NOTUM | |
| SCHEMBL10545373 | 0.61 | ALDH1A1 (0.73) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005024755-A2 | MEDICAMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS OR DIABETES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2005-03-17 | — | — | WO | disclosed |