Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 5/20 | 0.58 |
| ▸ | CTSL | P07711 | 5/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428726 | 0.84 | SGMS2 (0.57) | CTSVCTSLFOLH1PTGER1GAA | |
| SCHEMBL28907176 | 0.82 | C5AR1 (0.61) | CTSVCTSLMEN1KMT2AL3MBTL1 | |
| SCHEMBL20400859 | 0.81 | NPC1 (0.51) | CTSVCTSLMCL1FOLH1PTGER1 | |
| SCHEMBL8168015 | 0.81 | MCL1 (0.64) | CTSVCTSLMCL1FOLH1PTGER1 | |
| SCHEMBL4756552 | 0.80 | MAOB (0.63) | CTSVCTSLMCL1FOLH1SMN1; SMN2 | |
| SCHEMBL5583147 | 0.80 | MCL1 (0.63) | MCL1FOLH1PTGER1SMN1; SMN2GAA | |
| SCHEMBL20400951 | 0.80 | CTSV (0.50) | CTSVCTSLMCL1FOLH1PTGER1 | |
| SCHEMBL10089235 | 0.80 | FOLH1 (0.69) | MCL1FOLH1PTGER1SGMS2MAOB | |
| SCHEMBL31550547 | 0.79 | HDAC8 (0.60) | CTSVCTSLMCL1FOLH1SMN1; SMN2 | |
| SCHEMBL6404086 | 0.79 | HDAC8 (0.60) | CTSVCTSLMCL1FOLH1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050221318-A1 | Building block forming a c-c bond upon reaction | NUEVOLUTION A/S (DK) | 2005-10-06 | — | — | US | disclosed |
| EP-1490384-A2 | A BUILDING BLOCK FORMING A C-C BOND UPON REACTION | Nuevolution A/S (DK) | 2004-12-29 | — | — | EP | disclosed |
| EP-1487848-A2 | A BUILDING BLOCK FORMING A C=C DOUBLE BOND UPON REACTION | Nuevolution A/S (DK) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003078445-A2 | A BUILDING BLOCK FORMING A C=C DOUBLE BOND UPON REACTION | NUEVOLUTION A/S (DK) | 2003-09-25 | — | — | WO | disclosed |
| WO-2003078050-A2 | A BUILDING BLOCK FORMING A C-C BOND UPON REACTION | NUEVOLUTION A/S (DK) | 2003-09-25 | — | — | WO | disclosed |