Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.52 |
| ▸ | STAMBP | O95630 | 2/20 | 0.52 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.52 |
| ▸ | TTK | P33981 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331515 | 0.83 | TTK (0.49) | ALDH1A1PSMD14STAMBPCOPS5TTK | |
| SCHEMBL6426151 | 0.83 | HPGD (0.58) | ALDH1A1PSMD14STAMBPHPGDGAA | |
| SCHEMBL6428249 | 0.81 | PSMD14 (0.52) | ALDH1A1PSMD14STAMBPGAALMNA | |
| SCHEMBL4150719 | 0.78 | CA12 (0.48) | MAPK1 | |
| SCHEMBL6427786 | 0.76 | PSMD14 (0.54) | ALDH1A1PSMD14STAMBPCOPS5HPGD | |
| SCHEMBL4151588 | 0.76 | HPGDS (0.47) | HPGDRAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL4341021 | 0.75 | MAPT (0.49) | ALDH1A1TTKHPGDGAALMNA | |
| SCHEMBL6426335 | 0.74 | KMT2A (0.46) | ALDH1A1TTKHPGDGAALMNA | |
| SCHEMBL6427310 | 0.74 | CNR1 (0.44) | MAPK1RAB9ANPC1KDM4E | |
| SCHEMBL4341067 | 0.73 | RAB9A (0.46) | ALDH1A1TTKHPGDGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429609-B2 | Pyrazole compound and medicinal composition containing the same | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-09-30 | — | — | US | disclosed |
| US-7429609-B2 | Pyrazole compound and medicinal composition containing the same | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-09-30 | — | — | US | disclosed |
| US-20050261339-A1 | Pyrazole compound and medicinal composition containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261339-A1 | Pyrazole compound and medicinal composition containing the same | CNKSR1, NR3C2, CSNK2B | ALDH1A1 2713/4885PSMD14 4340/4885STAMBP 2938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.