Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | FABP1 | P07148 | 1/20 | 0.47 |
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427163 | 0.87 | ALDH1A1 (0.62) | ALDH1A1POLBCA12CA1CA2 | |
| SCHEMBL12443384 | 0.87 | ALDH1A1 (0.62) | ALDH1A1KDM4EPOLBL3MBTL1CA12 | |
| SCHEMBL6429493 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBLMNAHTT | |
| SCHEMBL6427510 | 0.85 | FAAH (0.57) | ALDH1A1KDM4EPOLBL3MBTL1CA12 | |
| SCHEMBL6428095 | 0.81 | ALDH1A1 (0.61) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL6429461 | 0.79 | POLB (0.70) | ALDH1A1POLBCA12CA1CA2 | |
| SCHEMBL6427441 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBL3MBTL1CA12 | |
| SCHEMBL31349252 | 0.75 | KCNJ1 (0.53) | ALDH1A1KDM4EPOLBL3MBTL1CA12 | |
| SCHEMBL2925701 | 0.74 | ALDH1A1 (0.59) | ALDH1A1KDM4EL3MBTL1CA12CA2 | |
| SCHEMBL6428414 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KDM4EPOLBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222408-A1 | Heterocyclic amides with anti-tuberculosis activity | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222408-A1 | Heterocyclic amides with anti-tuberculosis activity | TST, KAT5, NDUFS5 | ALDH1A1 2116/4885KDM4E 2025/4885POLB 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.