SCHEMBL11599863

SCHEMBL11599863

CCC(C)Oc1cccc(NC(=O)c2ccccc2C)c1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
F2R P25116 2/20 0.60
POLB P06746 4/20 0.60
KMT2A Q03164 4/20 0.60
KCNK3 O14649 3/20 0.60
KCNK9 Q9NPC2 3/20 0.60
RAB9A P51151 6/20 0.59
PKM P14618 1/20 0.59
SMN1; SMN2 Q16637 4/20 0.56
ALDH1A1 P00352 3/20 0.56
MEN1 O00255 2/20 0.55
HPGD P15428 2/20 0.55
NPC1 O15118 4/20 0.51
TP53 P04637 1/20 0.51
THRB P10828 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MAPT P10636 1/20 0.51
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mepronil SCHEMBL18447 0.88 KCNK3 (0.67) F2RPOLBKMT2AKCNK3KCNK9
Mepronil SCHEMBL29453871 0.88 KCNK3 (0.67) F2RPOLBKMT2AKCNK3KCNK9
Mepronil SCHEMBL20522512 0.88 KCNK3 (0.67) F2RPOLBKMT2AKCNK3KCNK9
Mepronil SCHEMBL30731287 0.88 KCNK3 (0.67) F2RPOLBKMT2AKCNK3KCNK9
SCHEMBL11588011 0.86 KMT2A (0.54) POLBKMT2AKCNK3KCNK9RAB9A
Mepronil SCHEMBL6429840 0.84 KCNK3 (0.61) F2RPOLBKMT2AKCNK3KCNK9
SCHEMBL11780348 0.83 POLB (0.67) F2RPOLBKMT2AKCNK3KCNK9
SCHEMBL4436642 0.81 KCNK3 (0.77) POLBKMT2AKCNK3KCNK9RAB9A
SCHEMBL11784409 0.81 LMNA (0.70) F2RPOLBKMT2AKCNK3KCNK9
SCHEMBL11779049 0.80 THRB (0.69) F2RPOLBKMT2AKCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3985804-A Agricultural substituted 2-methylbenzanilide germicide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-10-12 US claimed
US-4069335-A BENZANILIDES, FUNGICIDES KUMIAL CHEMICAL INDUSTRY CO., LTD. (JA) 1978-01-17 US disclosed