Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27670739 | 0.84 | CYP3A4 (0.30) | CYP3A4 | |
| SCHEMBL9555423 | 0.83 | TSHR (0.36) | TSHRACHECYP3A4GABRA1GABRB2 | |
| SCHEMBL28613862 | 0.82 | GABRA1 (0.35) | TSHRACHECYP3A4GABRA1GABRB2 | |
| SCHEMBL6831708 | 0.82 | GABRA1 (0.35) | TSHRACHECYP3A4GABRA1GABRB2 | |
| SCHEMBL29105562 | 0.79 | GABRA1 (0.33) | TSHRACHECYP3A4GABRA1GABRB2 | |
| SCHEMBL10918052 | 0.77 | KIF11 (0.31) | TSHRACHE | |
| SCHEMBL189760 | 0.77 | GABRA1 (0.32) | TSHRACHEGABRA1GABRB2 | |
| SCHEMBL7800891 | 0.76 | L3MBTL1 (0.35) | TSHRACHEGABRA1GABRB2L3MBTL1 | |
| SCHEMBL17966616 | 0.75 | ALOX15 (0.36) | TSHRCYP3A4ALDH1A1L3MBTL1CA1 | |
| SCHEMBL7031498 | 0.74 | MEN1 (0.35) | TSHRALDH1A1L3MBTL1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608704-A2 | THIOPHOSPHINE COMPOUNDS AND METHOD OF MAKING POLYMERISABLE COMPOSITIONS CONTAINING THEM AND THEIR USE FOR MAKING OPHTALMIC LENSES | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004085447-A2 | THIOPHOSPHINE COMPOUNDS AND METHOD OF MAKING POLYMERISABLE COMPOSITIONS CONTAINING THEM AND THEIR USE FOR MAKING OPHTALMIC LENSES | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2004-10-07 | — | — | WO | disclosed |