Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Fluoride Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL1634173 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL108667 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL28175694 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL29859 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL10339061 | 0.82 | CA4 (0.50) | — | |
| Fluoride Ion SCHEMBL7198266 | 0.78 | — | — | |
| Fluoride Ion SCHEMBL28416172 | 0.78 | — | — | |
| Fluoride Ion SCHEMBL1532630 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL10945206 | 0.67 | — | — | |
| Fluoride Ion SCHEMBL18128881 | 0.67 | CA4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566367-A1 | TOOTHBRUSH | The Gillette Company (US) | 2013-03-13 | — | — | EP | disclosed |
| US-8129444-B2 | Self-adhesive dental materials | 3M ESPE AG (DE) | 2012-03-06 | — | — | US | disclosed |
| WO-2011140346-A1 | TOOTHBRUSH | THE GILLETTE COMPANY (US) | 2011-11-10 | — | — | WO | disclosed |
| US-20060004122-A1 | Self-adhesive dental materials | 3M ESPE AG (DE) | 2006-01-05 | — | — | US | disclosed |
| US-20040110864-A1 | Self-adhesive dental materials | 3M ESPE AG (DE) | 2004-06-10 | — | — | US | disclosed |