Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.36 |
| ▸ | SCN4A | P35499 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428408 | 0.85 | CRHR1 (0.38) | CRHR1SCN9ASCN5ASCN4A | |
| SCHEMBL6430833 | 0.80 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL5842899 | 0.76 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL6393222 | 0.73 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL8344779 | 0.71 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL5600147 | 0.70 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL5843912 | 0.70 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL5845899 | 0.69 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL6428206 | 0.69 | SCN9A (0.35) | SCN9ASCN5A | |
| SCHEMBL5844056 | 0.68 | CRHR1 (0.62) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |