Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27309558 | 0.76 | GRIN2D (0.32) | S1PR4LMNAMAPTHTTGRIN2D | |
| SCHEMBL11679839 | 0.76 | POLB (0.32) | POLB | |
| SCHEMBL5844444 | 0.73 | MAPT (0.37) | MAPTL3MBTL1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5845662 | 0.70 | CYP19A1 (0.44) | — | |
| SCHEMBL20595552 | 0.70 | ALDH1A1 (0.45) | LMNAMAPTHTTPOLBL3MBTL1 | |
| SCHEMBL30014602 | 0.70 | ALDH1A1 (0.45) | LMNAMAPTHTTPOLBL3MBTL1 | |
| SCHEMBL5843301 | 0.69 | HCAR3 (0.41) | LMNAMAPTHTTPOLBL3MBTL1 | |
| SCHEMBL1625178 | 0.69 | ALDH1A1 (0.47) | LMNAMAPTHTTPOLBL3MBTL1 | |
| SCHEMBL563664 | 0.69 | ALDH1A1 (0.50) | S1PR4LMNAMAPTHTTPOLB | |
| SCHEMBL29779688 | 0.69 | ALDH1A1 (0.47) | LMNAMAPTHTTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032846-A1 | Corticotropin releasing factor antagonists | PFIZER INC. | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032846-A1 | Corticotropin releasing factor antagonists | CRH, CRHR2, CRHR1 | S1PR4 902/4885LMNA 4152/4885MAPT 1457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.