Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | WEE1 | P30291 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 5/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430581 | 0.77 | PDE11A (0.40) | MAPTWEE1MEN1ALDH1A1RAB9A | |
| SCHEMBL14215793 | 0.64 | FABP4 (0.61) | RXFP1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL6430582 | 0.61 | ACP1 (0.40) | MAPTMEN1MAPK1KMT2AMAPK8 | |
| SCHEMBL5871615 | 0.60 | PDE11A (0.49) | MAPTNPY5RMEN1ALDH1A1KMT2A | |
| SCHEMBL14215835 | 0.59 | MAPT (0.46) | RXFP1MAPTMEN1KMT2AGFER | |
| SCHEMBL23412937 | 0.58 | DGAT1 (0.47) | MAPTKDM4EMEN1ALDH1A1MAPK1 | |
| SCHEMBL30097592 | 0.58 | DGAT1 (0.47) | MAPTKDM4EMEN1ALDH1A1MAPK1 | |
| SCHEMBL5872038 | 0.58 | PDE11A (0.66) | MAPTWEE1MEN1ALDH1A1MAPK1 | |
| SCHEMBL14189060 | 0.58 | GRIK1 (0.47) | RXFP1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL8286065 | 0.58 | PDE11A (0.46) | KDM4EMEN1ALDH1A1KMT2AAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900205-B2 | 1,8-Naphthyridine derivatives and their use to treat diabetes and related disorders | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-05-31 | — | — | US | disclosed |