SCHEMBL7581317

SCHEMBL7581317

C=CCSc1nnsc1SCC=C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8536797 0.78 ALDH1A1 (0.36) SMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL6431331 0.78 MEN1 (0.33) SMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL7790910 0.78 ALDH1A1 (0.36) ALDH1A1MEN1KMT2A
SCHEMBL7081943 0.78 LMNA (0.36) ALDH1A1MEN1KMT2A
SCHEMBL8536794 0.78 ALDH1A1 (0.33) SMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL7594898 0.77 ALDH1A1 (0.36) ALDH1A1
SCHEMBL8599818 0.71
SCHEMBL7677695 0.69 L3MBTL1 (0.42) SMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL3763261 0.68 ALDH1A1 (0.34) ALDH1A1
SCHEMBL29082169 0.68 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1231256-A2 Automatic transmission lubricant composition with improved anti-wear properties ETHYL CORPORATION (US) 2002-08-14 EP claimed
EP-0284676-B1 MERCAPTO-THIADIAZOLE REACTION PRODUCTS AS MULTIFUNCTIONAL LUBRICANT ADDITIVES AND COMPOSITIONS THEREOF MOBIL OIL CORPORATION (US) 1991-12-04 EP claimed
EP-0284676-A1 Mercapto-thiadiazole reaction products as multifunctional lubricant additives and compositions thereof MOBIL OIL CORPORATION (US) 1988-10-05 EP claimed
US-4661273-A WEAR RESISTANCE, OXIDATIN RESISTANCE MOBIL OIL COMPANY (US) 1987-04-28 US claimed
EP-0778335-B1 Grease composition with improved antiwear properties CHEVRON ORONITE CO (US) 2002-08-07 EP disclosed
US-5641730-A EFFECTIVE STABILIZERS COMPRISING THE MIXTURE OF ALKALI METAL BORATES AND A THIADIAZOLE COMPOUNDS CHEVRON CHEMICAL COMPANY 1997-06-24 US disclosed
EP-0778335-A2 Grease composition with improved antiwear properties CHEVRON CHEMICAL COMPANY (US) 1997-06-11 EP disclosed
US-4432847-A AND UNSATURATED HYDROCARBON TO FORM REACTION PRODUCT, THEN OXIDATION STANDARD OIL COMPANY (INDIANA) (US) 1984-02-21 US disclosed