Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431706 | 1.00 | GGT1 (0.34) | GGT1FOLH1CPB2SIRT6SIRT1 | |
| SCHEMBL146727 | 0.77 | GGT1 (0.55) | GGT1FOLH1CPB2 | |
| SCHEMBL6890284 | 0.77 | GGT1 (0.55) | GGT1FOLH1CPB2 | |
| SCHEMBL27482919 | 0.74 | SIRT6 (0.49) | GGT1FOLH1CPB2SIRT6SIRT1 | |
| SCHEMBL27481855 | 0.74 | SIRT6 (0.49) | GGT1FOLH1CPB2SIRT6SIRT1 | |
| SCHEMBL6431464 | 0.73 | GSR (0.47) | CPB2NOS1 | |
| SCHEMBL6862207 | 0.73 | GSR (0.47) | CPB2NOS1 | |
| SCHEMBL5499164 | 0.73 | GSR (0.47) | CPB2NOS1 | |
| SCHEMBL6316197 | 0.72 | FOLH1 (0.54) | GGT1FOLH1CPB2SIRT6SIRT1 | |
| SCHEMBL6859366 | 0.72 | FOLH1 (0.54) | GGT1FOLH1CPB2SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254161-B1 | AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE | BASILEA PHARMACEUTICA AG (CH) | 2005-04-20 | — | — | EP | claimed |
| US-6849709-B2 | Aerothricin derivatives | BASILEA PHARMACEUTICA AG (CH) | 2005-02-01 | — | — | US | claimed |
| EP-1254161-A2 | AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE | Basilea Pharmaceutica AG (CH) | 2002-11-06 | — | — | EP | claimed |
| US-20010031728-A1 | Aerothricin derivatives | F. HOFFMANN-LA ROCHE AG A SWISS COMPANY (CH) | 2001-10-18 | — | — | US | claimed |
| WO-2001053322-A2 | AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE | BASILEA PHARMACEUTICA AG (CH) | 2001-07-26 | — | — | WO | claimed |
| EP-1254161-B1 | AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE | BASILEA PHARMACEUTICA AG (CH) | 2005-04-20 | — | — | EP | disclosed |
| US-6849709-B2 | Aerothricin derivatives | BASILEA PHARMACEUTICA AG (CH) | 2005-02-01 | — | — | US | disclosed |
| EP-1254161-A2 | AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE | Basilea Pharmaceutica AG (CH) | 2002-11-06 | — | — | EP | disclosed |
| US-20010031728-A1 | Aerothricin derivatives | F. HOFFMANN-LA ROCHE AG A SWISS COMPANY (CH) | 2001-10-18 | — | — | US | disclosed |
| WO-2001053322-A2 | AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE | BASILEA PHARMACEUTICA AG (CH) | 2001-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031728-A1 | Aerothricin derivatives | CIAPIN1, CYP27A1, CYP46A1 | GGT1 1468/4885FOLH1 1448/4885CPB2 2101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.