Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16561436 | 0.83 | CA12 (0.53) | GSTP1CA12CA1CA4CA9 | |
| SCHEMBL12517362 | 0.83 | CYP19A1 (0.59) | GSTP1CA12CA1CA4CA9 | |
| SCHEMBL18737335 | 0.83 | CYP19A1 (0.50) | GSTP1CA12CA1CA4CA9 | |
| SCHEMBL5704242 | 0.83 | GSTP1 (0.46) | GSTP1CA12CA1CA4CA9 | |
| SCHEMBL4398919 | 0.81 | PKM (0.56) | GSTP1CA12CA1CA4CA9 | |
| SCHEMBL24733164 | 0.81 | CHRNB2 (0.50) | GSTP1CA12CA1CA4CA9 | |
| SCHEMBL9718528 | 0.80 | CA12 (0.50) | GSTP1CA12CA1CA4CA9 | |
| SCHEMBL20273256 | 0.80 | PARP10 (0.59) | GSTP1CA12CA1CA4CA9 | |
| SCHEMBL9155792 | 0.80 | L3MBTL1 (0.61) | GSTP1CA12CA1CA4CA9 | |
| SCHEMBL28721563 | 0.80 | CA12 (0.50) | GSTP1CA12CA1CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989973-B1 | CHALCONES HAVING ANTIPROLIFERATIVE ACTIVITY | INDENA SPA (IT) | 2005-08-31 | — | — | EP | disclosed |
| US-6423740-B1 | ANTICARCINOGENIC AGENTS | INDENA S.P.A. (IT) | 2002-07-23 | — | — | US | disclosed |
| US-6147082-A | 1,3-DIPHENYL-2-PROPENE-1-ONE DERIVATIVES; TREATING OR PREVENTING NEOPLASMS, MENOPAUSAL DISORDERS, AND OSTEOPOROSIS IN A MAMMAL | INDENA S.P.A (IT) | 2000-11-14 | — | — | US | disclosed |
| EP-0989973-A1 | CHALCONES HAVING ANTIPROLIFERATIVE ACTIVITY | INDENA S.p.A. (IT) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998058913-A1 | CHALCONES HAVING ANTIPROLIFERATIVE ACTIVITY | INDENA S.P.A. (IT) | 1998-12-30 | — | — | WO | disclosed |