Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046498 | 0.86 | HRH3 (0.47) | HRH3ALDH1A1TSHRCYP3A4CYP2C19 | |
| SCHEMBL1696905 | 0.81 | ALDH1A1 (0.56) | HRH3ALDH1A1TSHRCYP3A4CYP2C19 | |
| SCHEMBL10469275 | 0.78 | HRH3 (0.49) | HRH3ALDH1A1TSHRCYP3A4CYP2C19 | |
| SCHEMBL31510409 | 0.78 | ALDH1A1 (0.53) | HRH3ALDH1A1TSHRCYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL9596868 | 0.77 | HRH3 (0.48) | HRH3ALDH1A1TSHRCYP3A4CYP2C19 | |
| SCHEMBL5813245 | 0.77 | RAB9A (0.53) | HRH3ALDH1A1TSHRCYP3A4CYP2C19 | |
| SCHEMBL6432782 | 0.76 | FKBP1A (0.45) | HRH3ALDH1A1TSHRCYP3A4CYP2C19 | |
| SCHEMBL3424629 | 0.76 | ALDH1A1 (0.51) | HRH3ALDH1A1TSHRCYP3A4CYP2C19 | |
| SCHEMBL5954184 | 0.76 | PHGDH (0.55) | HRH3ALDH1A1TSHRCYP3A4CYP2C19 | |
| SCHEMBL321368 | 0.75 | ALDH1A1 (0.67) | ALDH1A1TSHRCYP3A4CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5667541-A | BINDER FROM FREE RADICAL POLYMERIZED ACRYLATED RESINS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-09-16 | — | — | US | claimed |
| EP-0654323-B1 | Coatable composition and methods of making abrasive articles | MINNESOTA MINING & MFG (US) | 2005-04-20 | — | — | EP | disclosed |
| US-5667541-A | BINDER FROM FREE RADICAL POLYMERIZED ACRYLATED RESINS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0654323-A1 | Coatable compositions, abrasive articles made therefrom, and methods of making and using same | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-05-24 | — | — | EP | disclosed |
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4582862-A | QUICK-SETTING PRINTING INKS BASED ON ACRYLATED RESINS | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0088050-A2 | Coloured photo-hardenable composition | CIBA-GEIGY AG (CH) | 1983-09-07 | — | — | EP | disclosed |