Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.70 |
| ▸ | CCR2 | P41597 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439399 | 0.93 | F10 (0.60) | F10CCR2SRD5A2FFAR1PPARG | |
| SCHEMBL6432803 | 0.90 | CCR2 (0.70) | F10CCR2SRD5A2FFAR1FFAR4 | |
| SCHEMBL6432567 | 0.86 | F10 (0.66) | F10CCR2F2CNR1 | |
| SCHEMBL6432419 | 0.85 | F10 (0.71) | F10CCR2F2SRD5A2PPARG | |
| SCHEMBL7430298 | 0.82 | F10 (0.83) | F10F2SRD5A2PPARG | |
| Acetic Acid SCHEMBL7717345 | 0.80 | F10 (0.95) | F10F2 | |
| SCHEMBL6433751 | 0.77 | F10 (0.67) | F10CCR2F2 | |
| SCHEMBL6433289 | 0.77 | NOD2 (0.67) | F10CCR2F2 | |
| SCHEMBL6433615 | 0.76 | CCR2 (0.58) | F10CCR2CNR1 | |
| SCHEMBL6432762 | 0.76 | CCR2 (0.58) | F10CCR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |