SCHEMBL6433059

SCHEMBL6433059

OCCOCC(CO)OCCO

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
MAPK1 P28482 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 2/20 0.36
USP2 O75604 1/20 0.33
THRB P10828 1/20 0.33
HTT P42858 1/20 0.33
MAPT P10636 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
LPAR1 Q92633 4/20 0.31
LPAR3 Q9UBY5 4/20 0.31
LPAR2 Q9HBW0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13028968 0.95 MEN1 (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL9286584 0.91 TSHR (0.46) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL1219820 0.91 MEN1 (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL21855420 0.91 MEN1 (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL28098697 0.91 MEN1 (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL9418830 0.90 TSHR (0.36) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL1357542 0.90 TSHR (0.47) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL9559516 0.89 TSHR (0.38) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL5502602 0.87 TSHR (0.45) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL14644928 0.87 TSHR (0.45) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304604-A1 ORGANOSILANES FOR THE TREATMENT OF INFECTIONS TOPIKOS SCIENTIFIC, INC. (US) 2025-10-02 US disclosed
US-12180239-B2 Organosilanes for the treatment of infections TOPIKOS SCIENTIFIC, INC. (US) 2024-12-31 US disclosed
US-20230295195-A1 ANTIMICROBIAL ORGANOSILANES Tipikos Pharmaceuticals, Inc. (US) 2023-09-21 US disclosed
EP-3298119-B2 SURFACTANT AND DETERGENT COMPOSITIONS CONTAINING ETHOXYLATED GLYCERINE PROCTER & GAMBLE (US) 2022-05-25 EP disclosed
US-20210253607-A1 ORGANOSILANES FOR THE TREATMENT OF INFECTIONS TOPIKOS PHARMACEUTICALS, INC. (US) 2021-08-19 US disclosed
US-20200248102-A1 METHOD OF MAKING SURFACTANT COMPOSITIONS AND DETERGENT COMPOSITIONS PROCTER & GAMBLE (US) 2020-08-06 US disclosed
US-10640733-B2 Surfactant and detergent compositions containing ethoxylated glycerine The Procter & Gamble Company LLC (US) 2020-05-05 US disclosed
US-10640734-B2 Surfactant and detergent compositions containing ethoxylated glycerine THE PROCTER & GAMBLE COMPANY (US) 2020-05-05 US disclosed
WO-2020082026-A1 ORGANOSILANES FOR THE TREATMENT OF INFECTIONS TOPIKOS PHARMACEUTICALS, INC. (US) 2020-04-23 WO disclosed
EP-3298119-B1 SURFACTANT AND DETERGENT COMPOSITIONS CONTAINING ETHOXYLATED GLYCERINE PROCTER & GAMBLE (US) 2019-04-24 EP disclosed
US-20100286101-A1 PHARMACEUTICAL COMPOSITION INCLUDING A CORTICOSTEROID AND A VITAMIN D ANALOG HAVING IMPROVED STABILITY CARBOL JASON 2010-11-11 US disclosed
CN-101810544-A Method of making up and the device of realizing this method are made up in the using base layer photoactivation OREAL 2010-08-25 CN disclosed
CN-101810545-A The method and the photosensitization composition for cosmetics of making up made up in photoactivation OLIER PARIS CO LTD 2010-08-25 CN disclosed
EP-1172400-B1 THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY YUPO CORP (JP) 2005-12-28 EP disclosed
US-6586106-B2 Ink transfer, adhesion and aging stability, and being satisfactory in back ghost when offset printing using oxidation polymerization type ink is performed on both faces YUPO CORPORATION (JP) 2003-07-01 US disclosed
US-20020054991-A1 Thermoplastic resin film satisfactory in printability YUPO CORPORATION (JP) 2002-05-09 US disclosed
EP-1172400-A1 THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY Yupo Corporation (JP) 2002-01-16 EP disclosed
US-5880130-A TREATMENT OF CELL-PROLIFERATION DISEASES ZENECA LIMITED (GB) 1999-03-09 US disclosed
EP-0733045-A1 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS ZENECA LIMITED (GB) 1996-09-25 EP disclosed
WO-1995015952-A1 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS ZENECA LIMITED (GB) 1995-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210253607-A1 ORGANOSILANES FOR THE TREATMENT OF INFECTIONS ASNS, ACMSD, ARG1 TSHR 4175/4885MAPK1 3834/4885MEN1 1482/4885
US-12180239-B2 Organosilanes for the treatment of infections ASNS, ACMSD, ARG1 TSHR 4175/4885MAPK1 3834/4885MEN1 1482/4885
US-20250304604-A1 ORGANOSILANES FOR THE TREATMENT OF INFECTIONS ASNS, ACMSD, ARG1 TSHR 4175/4885MAPK1 3834/4885MEN1 1482/4885
US-20100286101-A1 PHARMACEUTICAL COMPOSITION INCLUDING A CORTICOSTEROID AND A VITAMIN D ANALOG HAVING IMPROVED STABILITY CYP24A1, CYP2R1, VDR TSHR 1880/4885MAPK1 4138/4885MEN1 3298/4885
US-20230295195-A1 ANTIMICROBIAL ORGANOSILANES ARG1, ACMSD, AAAS TSHR 4128/4885MAPK1 3701/4885MEN1 2477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.