Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 10/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4642031 | 0.82 | FPR2 (0.39) | FPR2F2RL1ADRA2AADRA2BADRA2C | |
| SCHEMBL953334 | 0.80 | CHRM2 (0.43) | FPR2F2RL1ADRA2AADRA2BADRA2C | |
| SCHEMBL10686017 | 0.76 | CYP19A1 (0.45) | CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL8088802 | 0.76 | FPR2 (0.43) | FPR2F2RL1ADRA2AADRA2BADRA2C | |
| SCHEMBL5597421 | 0.76 | FPR2 (0.39) | FPR2F2RL1ADRA2AADRA2BADRA2C | |
| SCHEMBL10530699 | 0.75 | AAK1 (0.37) | FPR2F2RL1ADRA2AADRA2BADRA2C | |
| SCHEMBL8993022 | 0.75 | HTR2A (0.41) | ADRA2AADRA2BADRA2CCYP1A2CYP3A4 | |
| SCHEMBL4640751 | 0.73 | L3MBTL1 (0.42) | FPR2F2RL1ADRA2AADRA2BADRA2C | |
| SCHEMBL9803992 | 0.72 | CYP19A1 (0.43) | FPR2F2RL1ADRA2AADRA2BADRA2C | |
| SCHEMBL4642675 | 0.72 | ALDH1A1 (0.56) | FPR2ADRA2AADRA2BADRA2CCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492515-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN AROMATASE INHIBITOR AND AN ESTROGEN SUITABLE FOR HORMONE REPLACEMENT THERAPY FOR A MALE | JENCAP RESEARCH LTD. (CA) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082254-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN AROMATASE INHIBITOR AND AN ESTROGEN SUITABLE FOR HORMONE REPLACEMENT THERAPY FOR A MALE | JENCAP RESEARCH LTD. (CA) | 2003-10-09 | — | — | WO | disclosed |