Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344776 | 0.92 | CRHR1 (0.40) | ALDH1A1MAPTCRHR1MEN1KMT2A | |
| SCHEMBL6428203 | 0.88 | HPGD (0.33) | HPGDUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL6428374 | 0.87 | CRHR1 (0.38) | ALDH1A1CRHR1 | |
| SCHEMBL6429485 | 0.84 | TAS1R3 (0.35) | ALDH1A1POLBMAPTSMN1; SMN2CRHR1 | |
| Hydrochloric Acid SCHEMBL6430345 | 0.79 | KMT2A (0.32) | MAPTCRHR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6430340 | 0.79 | KMT2A (0.32) | MAPTCRHR1MEN1KMT2A | |
| SCHEMBL6428205 | 0.76 | CRHR1 (0.41) | MAPTCRHR1 | |
| SCHEMBL5844156 | 0.72 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL6445881 | 0.69 | PDGFRB (0.36) | HPGDUSP2ALDH1A1LMNAPOLB | |
| SCHEMBL5844732 | 0.69 | CRHR1 (0.51) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |