Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344776 | 0.84 | CRHR1 (0.40) | CRHR1MAPT | |
| SCHEMBL6428374 | 0.81 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL6428372 | 0.81 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL6433393 | 0.76 | HPGD (0.35) | CRHR1MAPT | |
| SCHEMBL6428203 | 0.73 | HPGD (0.33) | MAPT | |
| SCHEMBL6429485 | 0.73 | TAS1R3 (0.35) | CRHR1MAPT | |
| SCHEMBL8344779 | 0.71 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL5845505 | 0.71 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL6428379 | 0.69 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL7615786 | 0.68 | CRHR1 (0.50) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |