Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344776 | 0.95 | CRHR1 (0.40) | CRHR1ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6433393 | 0.87 | HPGD (0.35) | CRHR1ALDH1A1 | |
| SCHEMBL6429485 | 0.83 | TAS1R3 (0.35) | CRHR1ALDH1A1TRPV3TDP1TAS1R3 | |
| SCHEMBL6428205 | 0.81 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL6428203 | 0.78 | HPGD (0.33) | ALDH1A1 | |
| SCHEMBL6428379 | 0.76 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL8344779 | 0.72 | CRHR1 (0.47) | CRHR1ALDH1A1 | |
| SCHEMBL5843230 | 0.72 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL5843235 | 0.72 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL5599406 | 0.68 | CRHR1 (0.69) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |