Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE6C | P51160 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019550 | 0.85 | PDE5A (0.46) | NPSR1KMT2ALRRK2USP2HSD17B10 | |
| SCHEMBL7019558 | 0.79 | PARP1 (0.41) | NPSR1KMT2ALRRK2USP2HSD17B10 | |
| SCHEMBL29707546 | 0.70 | PDE5A (0.77) | KMT2AHPGDPDE5APDE6CMEN1 | |
| SCHEMBL145682 | 0.70 | PDE5A (0.77) | KMT2AHPGDPDE5APDE6CMEN1 | |
| SCHEMBL3671938 | 0.69 | PDE5A (0.63) | PDE5APDE6C | |
| SCHEMBL5085819 | 0.68 | PDE5A (0.65) | KMT2AHSD17B10PDE5APDE6CMEN1 | |
| SCHEMBL12125049 | 0.67 | NPSR1 (0.66) | NPSR1KMT2ALRRK2HSD17B10HPGD | |
| Citric Acid SCHEMBL18919600 | 0.67 | PDE5A (0.68) | PDE5APDE6C | |
| SCHEMBL8344627 | 0.67 | PDE5A (0.70) | PDE5APDE6C | |
| SCHEMBL25013643 | 0.66 | PDE5A (0.75) | KMT2AHPGDPDE5APDE6CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511494-A1 | ANDROGEN PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATING DEPRESSION | Unimed Pharmaceuticals, Inc. (US) | 2005-03-09 | — | — | EP | disclosed |
| WO-2004091631-A1 | ANDROGEN PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATING DEPRESSION | UNIMED PHARMACEUTICALS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |