Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438206 | 0.85 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL2558763 | 0.84 | MEN1 (0.49) | MEN1KMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL855675 | 0.81 | MEN1 (0.48) | MEN1KMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL27914054 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL14820451 | 0.77 | ZDHHC20 (0.50) | MEN1KMT2AALDH1A1 | |
| SCHEMBL19681586 | 0.77 | ZDHHC20 (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27988246 | 0.77 | ZDHHC20 (0.50) | ALDH1A1 | |
| SCHEMBL7115011 | 0.77 | MEN1 (0.44) | MEN1KMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL1018029 | 0.76 | MEN1 (0.49) | MEN1KMT2AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL24711859 | 0.75 | MEN1 (0.41) | MEN1KMT2AALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159317-B1 | NEW BIOMATERIALS | COMMW SCIENT IND RES ORG (AU) | 2005-02-09 | — | — | EP | disclosed |
| US-6503958-B2 | Porous polymers incorporating dihydroperfluoroalkyl acrylates and methacrylates | NOVARTIS AG (CH) | 2003-01-07 | — | — | US | disclosed |
| US-20020103538-A1 | Biomaterials | HUGHES TIMOTHY CHARLES (AU) | 2002-08-01 | — | — | US | disclosed |
| EP-1192194-A1 | PROCESS FOR THE MANUFACTURE OF MOLDINGS | Novartis AG (CH) | 2002-04-03 | — | — | EP | disclosed |
| EP-1159317-A1 | NEW BIOMATERIALS | Novartis AG (CH) | 2001-12-05 | — | — | EP | disclosed |
| US-6255360-B1 | FREE RADICAL POLYMERIZATION OF AN ACRYLIC MONOMER HAVING A FLUOROALKYL MOIETY, REMOVING INTERMINGLED SEPARATE SOLVENT PHASE AND AFTERTREATING IN ACIDIC OR BASIC MEDIUM | NOVARTIS AG (CH) | 2001-07-03 | — | — | US | disclosed |
| WO-2000078830-A1 | PROCESS FOR THE MANUFACTURE OF MOLDINGS | NOVARTIS AG (CH) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000049058-A1 | NEW BIOMATERIALS | NOVARTIS AG (CH) | 2000-08-24 | — | — | WO | disclosed |