SCHEMBL6433486

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6433263	0.86	PLAU (0.42)	PLAUNAPRTPLGPOLBHTR5A
	SCHEMBL13754214	0.85	ALDH1A1 (0.42)	PLAUNAPRTPLGALDH1A1HPGD
	SCHEMBL9907725	0.83	PLAU (0.49)	PLAUNAPRTTSHRPLGALDH1A1
	SCHEMBL27185299	0.83	NAPRT (0.47)	NAPRTTSHRALDH1A1POLBHPGD
	SCHEMBL17437241	0.80	PLAU (0.49)	PLAUNAPRTTSHRPLGALDH1A1
	SCHEMBL9907716	0.80	PLAU (0.52)	PLAUNAPRTTSHRPLGALDH1A1
	SCHEMBL4991890	0.78	TSHR (0.50)	NAPRTTSHRALDH1A1POLBL3MBTL1
	SCHEMBL9907662	0.77	HTR5A (0.56)	PLAUNAPRTTSHRPLGHTR5A
	SCHEMBL6437644	0.77	ALDH1A1 (0.53)	ALDH1A1POLBHPGDL3MBTL1MAPT
	Hydrochloric Acid SCHEMBL10456360	0.77	TSHR (0.48)	NAPRTTSHRALDH1A1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.