Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 6/20 | 0.46 |
| ▸ | CDC25B | P30305 | 6/20 | 0.46 |
| ▸ | CDC25C | P30307 | 5/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | BID | P55957 | 2/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2731945 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL40469 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL10618311 | 0.98 | CDC25A (0.43) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL9332691 | 0.83 | — | — | |
| SCHEMBL7058414 | 0.82 | CDC25A (0.41) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL5269756 | 0.79 | CDC25A (0.39) | CDC25ACDC25BCDC25CSCDPPARG | |
| SCHEMBL2128309 | 0.74 | GPR84 (0.65) | CDC25ACDC25BCDC25CSCDALDH1A1 | |
| SCHEMBL6478501 | 0.72 | SCD (0.43) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL14989170 | 0.68 | BID (0.51) | SCDRARBALDH1A1MEN1KMT2A | |
| SCHEMBL19406563 | 0.68 | BID (0.51) | SCDRARBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916843-B1 | Anti-inflammatory actions of cytochrome P450 expoxygenase-derived eicosanoids | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2005-07-12 | — | — | US | claimed |
| EP-1207877-A4 | ANTI-INFLAMMATORY ACTIONS OF CYTOCHROME P450 EPOXYGENASE-DERIVED EICOSANOIDS | BRIGHAM & WOMENS HOSPITAL (US) | 2004-06-09 | — | — | EP | claimed |
| EP-1207877-A1 | ANTI-INFLAMMATORY ACTIONS OF CYTOCHROME P450 EPOXYGENASE-DERIVED EICOSANOIDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001010438-A1 | ANTI-INFLAMMATORY ACTIONS OF CYTOCHROME P450 EPOXYGENASE-DERIVED EICOSANOIDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2001-02-15 | — | — | WO | claimed |
| US-6916843-B1 | Anti-inflammatory actions of cytochrome P450 expoxygenase-derived eicosanoids | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2005-07-12 | — | — | US | disclosed |
| EP-1207877-A4 | ANTI-INFLAMMATORY ACTIONS OF CYTOCHROME P450 EPOXYGENASE-DERIVED EICOSANOIDS | BRIGHAM & WOMENS HOSPITAL (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-1207877-A1 | ANTI-INFLAMMATORY ACTIONS OF CYTOCHROME P450 EPOXYGENASE-DERIVED EICOSANOIDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001010438-A1 | ANTI-INFLAMMATORY ACTIONS OF CYTOCHROME P450 EPOXYGENASE-DERIVED EICOSANOIDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2001-02-15 | — | — | WO | disclosed |