Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 6/20 | 0.46 |
| ▸ | CDC25B | P30305 | 6/20 | 0.46 |
| ▸ | CDC25C | P30307 | 5/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | BID | P55957 | 2/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40469 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL6433540 | 1.00 | CDC25A (0.46) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL10618311 | 0.98 | CDC25A (0.43) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL9332691 | 0.83 | — | — | |
| SCHEMBL7058414 | 0.82 | CDC25A (0.41) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL5269756 | 0.79 | CDC25A (0.39) | CDC25ACDC25BCDC25CSCDPPARG | |
| SCHEMBL2128309 | 0.74 | GPR84 (0.65) | CDC25ACDC25BCDC25CSCDALDH1A1 | |
| SCHEMBL6478501 | 0.72 | SCD (0.43) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL14989170 | 0.68 | BID (0.51) | SCDRARBALDH1A1MEN1KMT2A | |
| SCHEMBL19406563 | 0.68 | BID (0.51) | SCDRARBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116271263-B | Composite reinforced degradable material and preparation method and application thereof | 广州医科大学 | 2024-09-13 | — | — | CN | claimed |
| CN-116271263-A | Composite reinforced degradable material and preparation method and application thereof | 广州医科大学 | 2023-06-23 | — | — | CN | claimed |
| US-20230059978-A1 | LIVE CELL CONSTRUCTS FOR BIOSYNTHETIC MILK PRODUCTION AND RELATED PRODUCTS AND METHODS | GUILIANO SHAYNE (US) | 2023-02-23 | — | — | US | claimed |
| EP-4087915-A1 | LIVE CELL CONSTRUCTS FOR BIOSYNTHETIC MILK PRODUCTION AND RELATED PRODUCTS AND METHODS | Guiliano, Shayne (US) | 2022-11-16 | — | — | EP | claimed |
| WO-2021142241-A1 | LIVE CELL CONSTRUCTS FOR BIOSYNTHETIC MILK PRODUCTION AND RELATED PRODUCTS AND METHODS | GUILIANO SHAYNE (US) | 2021-07-15 | — | — | WO | claimed |
| EP-3515498-B1 | INHIBITORS OF GPR132 FOR USE IN PREVENTING AND/OR TREATING CHEMOTHERAPY-INDUCED NEUROPATHIC PAIN | FRAUNHOFER GES FORSCHUNG (DE) | 2021-03-03 | — | — | EP | claimed |
| EP-3515498-A1 | INHIBITORS OF GPR132 FOR USE IN PREVENTING AND/OR TREATING CHEMOTHERAPY-INDUCED NEUROPATHIC PAIN | Fraunhofer Gesellschaft zur Förderung der angewandten Forschung E.V. (DE) | 2019-07-31 | — | — | EP | claimed |
| US-20190211397-A1 | INHIBITORS OF GPR132 FOR USE IN PREVENTING AND/OR TREATING CHEMOTHERAPY-INDUCED NEUROPATHIC PAIN | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2019-07-11 | — | — | US | claimed |
| CN-109715212-A | For preventing and/or treating the GPR132 inhibitor of neuropathic pain caused by chemotherapy | 弗劳恩霍夫应用研究促进协会 | 2019-05-03 | — | — | CN | claimed |
| WO-2018055082-A1 | INHIBITORS OF GPR132 FOR USE IN PREVENTING AND/OR TREATING CHEMOTHERAPY-INDUCED NEUROPATHIC PAIN | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2018-03-29 | — | — | WO | claimed |
| EP-3299032-A1 | INHIBITORS OF GPR132 FOR USE IN PREVENTING AND/OR TREATING CHEMOTHERAPY-INDUCED NEUROPATHIC PAIN | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2018-03-28 | — | — | EP | claimed |
| CN-116271263-B | Composite reinforced degradable material and preparation method and application thereof | 广州医科大学 | 2024-09-13 | — | — | CN | disclosed |
| CN-116271263-B | Composite reinforced degradable material and preparation method and application thereof | 广州医科大学 | 2024-09-13 | — | — | CN | disclosed |
| CN-118542862-A | Application of pinocembrin in preparation of aromatic hydrocarbon receptor regulator | 中国科学院华南植物园 | 2024-08-27 | — | — | CN | disclosed |
| CN-117007728-A | Method for simultaneously analyzing common free oxidized lipid and precursor compound of breast milk or milk powder sample | 黑龙江飞鹤乳业有限公司 | 2023-11-07 | — | — | CN | disclosed |
| WO-2014111465-A1 | ISOMANNIDE DERIVATIVES AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | SANOFI (FR) | 2014-07-24 | — | — | WO | disclosed |
| EP-1931201-B1 | USE OF SEH INHIBITORS AS ANALGESICS | UNIV CALIFORNIA (US) | 2012-05-02 | — | — | EP | disclosed |
| US-20080249055-A1 | Use of Seh Inhibitors as Analgesics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-10-09 | — | — | US | disclosed |
| EP-1931201-A2 | USE OF SEH INHIBITORS AS ANALGESICS | The Regents of the University of California (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007022509-A2 | USE OF SEH INHIBITORS AS ANALGESICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249055-A1 | Use of Seh Inhibitors as Analgesics | EPHX1, FAAH, EPHX2 | CDC25A 2647/4885CDC25B 2286/4885CDC25C 3289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.