Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 6/20 | 0.41 |
| ▸ | CDC25B | P30305 | 6/20 | 0.41 |
| ▸ | CDC25C | P30307 | 5/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2731945 | 0.82 | CDC25A (0.46) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL6433540 | 0.82 | CDC25A (0.46) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL40469 | 0.82 | CDC25A (0.46) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL10618311 | 0.80 | CDC25A (0.43) | CDC25ACDC25BCDC25CSCDRARB | |
| SCHEMBL2128309 | 0.69 | GPR84 (0.65) | CDC25ACDC25BCDC25CSCDMEN1 | |
| SCHEMBL14989207 | 0.67 | BID (0.51) | SCDRARBMEN1ALDH1A1RARA | |
| SCHEMBL19406563 | 0.67 | BID (0.51) | SCDRARBMEN1ALDH1A1RARA | |
| SCHEMBL14989301 | 0.67 | BID (0.51) | SCDRARBMEN1ALDH1A1RARA | |
| SCHEMBL14989230 | 0.67 | BID (0.51) | SCDRARBMEN1ALDH1A1RARA | |
| SCHEMBL14989170 | 0.67 | BID (0.51) | SCDRARBMEN1ALDH1A1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926951-B1 | TREATING PULMONARY DISEASES MEDIATED BY POLYUNSATURATED LIPID METABOLITES AND ASSAYS FOR EPOXIDE HYDROLASE INHIBITORS | UNIV CALIFORNIA (US) | 2004-04-21 | — | — | EP | disclosed |
| EP-0926951-A4 | METHODS OF TREATING PULMONARY DISEASES MEDIATED BY POLYUNSATURATED LIPID METABOLITES AND ASSAYS FOR EPOXIDE HYDROLASE INHIBITORS | UNIV CALIFORNIA (US) | 2001-08-08 | — | — | EP | disclosed |
| US-6174695-B1 | DETERMINING INTRACELLULAR CHANGE IN CALCIUM LEVELS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-01-16 | — | — | US | disclosed |
| US-5955496-A | TREATING ADULT RESPIRATORY DISTRESS SYNDROME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-09-21 | — | — | US | disclosed |
| EP-0926951-A1 | METHODS OF TREATING PULMONARY DISEASES MEDIATED BY POLYUNSATURATED LIPID METABOLITES AND ASSAYS FOR EPOXIDE HYDROLASE INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998006261-A1 | METHODS OF TREATING PULMONARY DISEASES MEDIATED BY POLYUNSATURATED LIPID METABOLITES AND ASSAYS FOR EPOXIDE HYDROLASE INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-02-19 | — | — | WO | disclosed |