Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.65 |
| ▸ | PPARG | P37231 | 7/20 | 0.65 |
| ▸ | PPARD | Q03181 | 7/20 | 0.65 |
| ▸ | PPARA | Q07869 | 7/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TLR2 | O60603 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | FABP4 | P15090 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.65 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403682 | 0.82 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL25290273 | 0.81 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL23705769 | 0.81 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL25291231 | 0.81 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL25286532 | 0.81 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL23649545 | 0.81 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dotriacontanoic Acid SCHEMBL25298401 | 0.81 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Lignoceric Acid SCHEMBL23751106 | 0.81 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Sebacic Acid SCHEMBL23781711 | 0.81 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL25293218 | 0.81 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10125337-B2 | Branched diesters and methods of making and using the same | TRENT UNIVERSITY (CA) | 2018-11-13 | — | — | US | disclosed |
| US-10100317-B2 | Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-10-16 | — | — | US | disclosed |
| US-20170204415-A1 | Compositions of Matter that Reduce Pain, Shock, and Inflammation by Blocking Linoleic Acid Metabolites and Uses Thereof | UNIV TEXAS (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170137739-A1 | BRANCHED DIESTERS AND METHODS OF MAKING AND USING THE SAME | TRENT UNIVERSITY (CA) | 2017-05-18 | — | — | US | disclosed |
| US-9592301-B2 | Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof | UNIV TEXAS (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160045610-A1 | COMPOSITIONS OF MATTER THAT REDUCE PAIN, SHOCK, AND INFLAMMATION BY BLOCKING LINOLEIC ACID METABOLITES AND USES THEREOF | UNIV TEXAS (US) | 2016-02-18 | — | — | US | disclosed |
| US-9029342-B2 | Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-05-12 | — | — | US | disclosed |
| US-20140128588-A1 | COMPOSITIONS OF MATTER THAT REDUCE PAIN, SHOCK, AND INFLAMMATION BY BLOCKING LINOLEIC ACID METABOLITES AND USES THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-05-08 | — | — | US | disclosed |
| WO-2013123393-A1 | BIOBASED SEMI-SOLID LUBRICANT AND METHOD OF PREPARATION | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-08-22 | — | — | WO | disclosed |
| EP-2444388-A1 | Asymmetric esters of fatty acids useful as lubricants | Industrial Quimica Lasem, S.A. (ES) | 2012-04-25 | — | — | EP | disclosed |
| WO-2002066654-A2 | DRUG METABOLIZING ENZYMES | INCYTE GENOMICS, INC. (US) | 2002-08-29 | — | — | WO | disclosed |
| WO-2002026988-A9 | HUMAN DRUG METABOLIZING ENZYMES | INCYTE GENOMICS INC (US) | 2002-07-04 | — | — | WO | disclosed |
| WO-2002046426-A2 | POLYPEPTIDE SEQUENCES OF DRUG METABOLIZING ENZYMES AND POLYNUCLEOTIDE SEQUENCES CODING THEREFOR | INCYTE GENOMICS, INC. (US) | 2002-06-13 | — | — | WO | disclosed |
| WO-2002026988-A2 | HUMAN DRUG METABOLIZING ENZYMES | INCYTE GENOMICS, INC. (US) | 2002-04-04 | — | — | WO | disclosed |
| WO-2002012467-A2 | DRUG METABOLIZING ENZYMES | INCYTE GENOMICS, INC. (US) | 2002-02-14 | — | — | WO | disclosed |
| WO-2002004612-A2 | DRUG METABOLIZING ENZYMES | INCYTE GENOMICS, INC. (US) | 2002-01-17 | — | — | WO | disclosed |
| WO-2001090334-A2 | DRUG METABOLIZING ENZYMES | INCYTE GENOMICS, INC. (US) | 2001-11-29 | — | — | WO | disclosed |
| WO-2001079468-A2 | DRUG METABOLIZING ENZYMES | INCYTE GENOMICS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |
| WO-2001059127-A2 | DRUG METABOLIZING ENZYMES | INCYTE GENOMICS, INC. (US) | 2001-08-16 | — | — | WO | disclosed |
| WO-2001051638-A2 | DRUG METABOLIZING ENZYMES | INCYTE GENOMICS, INC. (US) | 2001-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10100317-B2 | Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof | FABP1, HSPBP1, LTA | GPR84 545/4885PPARG 312/4885PPARD 547/4885 |
| US-20170204415-A1 | Compositions of Matter that Reduce Pain, Shock, and Inflammation by Blocking Linoleic Acid Metabolites and Uses Thereof | FABP1, HSPBP1, LTA | GPR84 545/4885PPARG 312/4885PPARD 547/4885 |
| US-20140128588-A1 | COMPOSITIONS OF MATTER THAT REDUCE PAIN, SHOCK, AND INFLAMMATION BY BLOCKING LINOLEIC ACID METABOLITES AND USES THEREOF | FABP1, HSPBP1, LTA | GPR84 545/4885PPARG 312/4885PPARD 547/4885 |
| US-10125337-B2 | Branched diesters and methods of making and using the same | DGKG, SQLE, DGAT2 | GPR84 581/4885PPARG 145/4885PPARD 311/4885 |
| US-20170137739-A1 | BRANCHED DIESTERS AND METHODS OF MAKING AND USING THE SAME | ELOVL3, SCD, PTGER3 | GPR84 1391/4885PPARG 133/4885PPARD 231/4885 |
| US-20160045610-A1 | COMPOSITIONS OF MATTER THAT REDUCE PAIN, SHOCK, AND INFLAMMATION BY BLOCKING LINOLEIC ACID METABOLITES AND USES THEREOF | FABP1, HSPBP1, LTA | GPR84 545/4885PPARG 312/4885PPARD 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.