Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28062355 | 0.93 | KDM4E (0.53) | CES2CES1TBXAS1ALDH1A1MAPT | |
| SCHEMBL9717829 | 0.84 | TBXAS1 (0.53) | TBXAS1MTNR1AMTNR1B | |
| SCHEMBL7056287 | 0.78 | CES2 (0.62) | CES2CES1ALDH1A1MAPTKDM4E | |
| SCHEMBL6419216 | 0.78 | ALDH1A1 (0.57) | CES2CES1ALDH1A1MAPTKDM4E | |
| SCHEMBL28946747 | 0.78 | CES2 (0.49) | CES2CES1TBXAS1ALDH1A1MAPT | |
| SCHEMBL10361923 | 0.77 | KDM4E (0.52) | CES2CES1TBXAS1ALDH1A1MAPT | |
| SCHEMBL6319212 | 0.77 | NQO2 (0.50) | CES2CES1ALDH1A1MAPTKDM4E | |
| SCHEMBL6319210 | 0.77 | NQO2 (0.50) | CES2CES1ALDH1A1MAPTKDM4E | |
| SCHEMBL6319206 | 0.77 | NQO2 (0.50) | CES2CES1ALDH1A1MAPTKDM4E | |
| SCHEMBL5105348 | 0.77 | TBXAS1 (0.61) | CES2CES1TBXAS1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867323-B2 | Cross-coupling reaction of organosilicon nucleophiles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-03-15 | — | — | US | disclosed |