Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390607 | 0.90 | PLAU (0.44) | PLAUALDH1A1TAS2R14KDM4EKEAP1 | |
| SCHEMBL7400241 | 0.88 | PLAU (0.56) | TP53PLAUALDH1A1KDM4ELMNA | |
| SCHEMBL7375592 | 0.86 | ALDH1A1 (0.50) | PLAUALDH1A1TAS2R14KDM4E | |
| SCHEMBL6438243 | 0.86 | TP53 (0.45) | TP53PLAUALDH1A1TAS2R14KDM4E | |
| SCHEMBL7400877 | 0.85 | PLAU (0.46) | PLAUALDH1A1TAS2R14KDM4ELMNA | |
| Trifluoroacetic Acid SCHEMBL7451293 | 0.84 | PLAU (0.40) | TP53PLAUALDH1A1TAS2R14KDM4E | |
| SCHEMBL7409426 | 0.84 | PLAU (0.49) | PLAUALDH1A1TAS2R14KDM4ELMNA | |
| SCHEMBL7505548 | 0.83 | PLAU (0.47) | TP53PLAUALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7499923 | 0.83 | PLAU (0.47) | TP53PLAUALDH1A1KDM4ELMNA | |
| SCHEMBL7403796 | 0.81 | PLAU (0.52) | PLAUALDH1A1KDM4ETSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026836-A1 | Composition for the treatment of damaged tissue | DACK KEVIN NEIL (GB) | 2005-02-03 | — | — | US | disclosed |
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026836-A1 | Composition for the treatment of damaged tissue | MMP1, SERPINE1, COL14A1 | TP53 298/4885PLAU 119/4885ALDH1A1 2641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.