Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242285 | 0.84 | ALDH1A1 (0.54) | MEN1KMT2ADHFRALDH1A1GAA | |
| SCHEMBL6032201 | 0.84 | DHFR (0.39) | DHFRALDH1A1GAABACE1CA1 | |
| SCHEMBL27875517 | 0.82 | DHFR (0.44) | DHFRALDH1A1CA1CA2CA9 | |
| SCHEMBL4621770 | 0.81 | DHFR (0.43) | DHFRALDH1A1TAAR1 | |
| SCHEMBL4985361 | 0.77 | DHFR (0.41) | MEN1KMT2ADHFRALDH1A1GAA | |
| SCHEMBL893078 | 0.74 | GAA (0.38) | MEN1KMT2AGAASMN1; SMN2HTT | |
| SCHEMBL27957814 | 0.73 | TSHR (0.46) | MEN1KMT2ADHFRALDH1A1GAA | |
| SCHEMBL13009249 | 0.72 | GAA (0.41) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL10813336 | 0.71 | ELANE (0.50) | MEN1KMT2AALDH1A1GAAELANE | |
| SCHEMBL7474629 | 0.71 | KMT2A (0.41) | MEN1KMT2AALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572802-A1 | STYRENIC POLYMER COMPOSITES | Crompton Corporation (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004058881-A1 | STYRENIC POLYMER COMPOSITES | CROMPTON CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |