Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189966 | 0.86 | CYP2C19 (0.43) | CYP2C19ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL6434414 | 0.84 | SLC6A2 (0.34) | CYP2C19ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL6435579 | 0.83 | ALDH1A1 (0.38) | CYP2C19ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL6525291 | 0.81 | CYP2C19 (0.39) | CYP2C19ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL369647 | 0.77 | CYP2C19 (0.47) | CYP2C19ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL939842 | 0.76 | CYP2C19 (0.50) | CYP2C19ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL8680427 | 0.76 | CYP2C19 (0.50) | CYP2C19ALDH1A1KDM4EMAPTALOX15 | |
| Methane SCHEMBL28626702 | 0.74 | CYP2C19 (0.48) | CYP2C19ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL6438862 | 0.74 | KDM4E (0.33) | CYP2C19ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL28089324 | 0.74 | CYP2C19 (0.44) | CYP2C19ALDH1A1KDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867323-B2 | Cross-coupling reaction of organosilicon nucleophiles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-03-15 | — | — | US | disclosed |
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | TST, HPD, PCNA | CYP2C19 1856/4885ALDH1A1 2157/4885KDM4E 2413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.