Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL22445050 | 1.00 | MEN1 (0.65) | MEN1KMT2ATHRBHTTMAPT | |
| Acetic Acid SCHEMBL896457 | 1.00 | MEN1 (0.65) | MEN1KMT2ATHRBHTTMAPT | |
| Acetic Acid SCHEMBL22444982 | 1.00 | MEN1 (0.65) | MEN1KMT2ATHRBHTTMAPT | |
| Acetic Acid SCHEMBL6435690 | 0.98 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| Acetic Acid SCHEMBL2863329 | 0.93 | CES2 (0.68) | MEN1KMT2ATHRBHTTMAPT | |
| Acetic Acid SCHEMBL4930252 | 0.93 | CES2 (0.68) | MEN1KMT2ATHRBHTTMAPT | |
| Acetic Acid SCHEMBL537713 | 0.93 | CES2 (0.68) | MEN1KMT2ATHRBHTTMAPT | |
| Acetic Acid SCHEMBL2400937 | 0.93 | CES2 (0.68) | MEN1KMT2ATHRBHTTMAPT | |
| Acetic Acid SCHEMBL138223 | 0.93 | CES2 (0.68) | MEN1KMT2ATHRBHTTMAPT | |
| Acetic Acid SCHEMBL3426392 | 0.93 | CES2 (0.68) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2450385-A1 | BINDER RESIN FOR CONDUCTIVE PASTE, CONDUCTIVE PASTE, AND SOLAR CELL ELEMENT | Sekisui Chemical Co., Ltd. (JP) | 2012-05-09 | — | — | EP | disclosed |
| US-20120037223-A1 | BINDER RESIN FOR CONDUCTIVE PASTE, CONDUCTIVE PASTE, AND SOLAR CELL ELEMENT | SEKISUI CHEMICAL CO., LTD. (JP) | 2012-02-16 | — | — | US | disclosed |