Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272640 | 0.87 | TSHR (0.44) | LMNATSHRTDP1 | |
| SCHEMBL17464894 | 0.86 | LMNA (0.46) | LMNATSHRTDP1 | |
| SCHEMBL16207737 | 0.84 | TSHR (0.42) | LMNATSHRTDP1 | |
| SCHEMBL497879 | 0.83 | LMNA (0.60) | LMNATSHRTDP1 | |
| SCHEMBL3671978 | 0.81 | LMNA (0.52) | LMNATSHRTDP1 | |
| SCHEMBL2024839 | 0.80 | LMNA (0.44) | LMNATSHRTDP1 | |
| SCHEMBL1614311 | 0.79 | LMNA (0.42) | LMNATSHRTDP1 | |
| SCHEMBL17464917 | 0.79 | LMNA (0.42) | LMNATSHRTDP1 | |
| SCHEMBL940428 | 0.78 | — | — | |
| SCHEMBL155021 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001072866-A1 | POLYURETHANE PREPARED FROM SORBITOL-BRANCHED POLYESTERS | CROMPTON CORPORATION (US) | 2001-10-04 | — | — | WO | claimed |
| US-20220388217-A1 | MANUFACTURING METHOD FOR THERMOPLASTIC RESIN COMPOSITION, MANUFACTURING METHOD FOR SHAPED BODY, AND FILM | KANEKA CORPORATION (JP) | 2022-12-08 | — | — | US | disclosed |
| CN-115380060-A | Method for producing thermoplastic resin composition, method for producing molded article, and film | 株式会社钟化 | 2022-11-22 | — | — | CN | disclosed |
| US-20200140702-A1 | CURING AGENT FOR COATING COMPOSITION FOR FORMING SELF-RESTORABLE LAYER, COATING COMPOSITION HAVING THE SAME AND METHOD FOR COATING AUTOMOBILE EXTERIOR USING THE SAME | NOROO BEE CHEMICAL CO., LTD. (KR) | 2020-05-07 | — | — | US | disclosed |
| US-20170298058-A1 | HETEROCYCLIC RING AND CARBOCYCLIC DERIVATIVE | SHIONOGI & CO (JP) | 2017-10-19 | — | — | US | disclosed |
| US-9550763-B2 | Heterocyclic ring and carbocyclic derivative | SHIONOGI & CO., LTD. (JP) | 2017-01-24 | — | — | US | disclosed |
| US-20160024072-A1 | Heterocyclic Ring and Carbocyclic Derivative | SHIONOGI & CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| EP-1115925-B1 | POLYESTERS CONTAINING NEOPENTYL GLYCOL AND FIBERS FORMED THEREFROM | EASTMAN CHEM CO (US) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298058-A1 | HETEROCYCLIC RING AND CARBOCYCLIC DERIVATIVE | P2RX3, P2RX7, P2RX2 | LMNA 3635/4885TSHR 737/4885TDP1 4738/4885 |
| US-20160024072-A1 | Heterocyclic Ring and Carbocyclic Derivative | P2RX3, P2RX7, P2RX2 | LMNA 3635/4885TSHR 737/4885TDP1 4738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.