Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.62 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.54 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439252 | 0.87 | CYP19A1 (0.78) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL7083829 | 0.81 | AR (0.65) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL13415930 | 0.81 | CYP17A1 (0.52) | SERPINA6ALDH1A1ESR1CYP19A1AR | |
| SCHEMBL6448737 | 0.81 | ESR1 (0.54) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL6448612 | 0.81 | ESR1 (0.54) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL6450159 | 0.81 | ESR1 (0.54) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL6446120 | 0.79 | LMNA (0.48) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL11017258 | 0.77 | CYP19A1 (0.60) | SHBGSERPINA6ALDH1A1CYP19A1LMNA | |
| SCHEMBL6436205 | 0.77 | MAPT (0.49) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| Nandrolone SCHEMBL12101449 | 0.77 | ALDH1A1 (1.00) | SHBGSERPINA6SLC22A1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113354-A1 | Bioavailable prodrugs of androgenic steroids and related method | ROBERTS WILLIAM J (US) | 2005-05-26 | — | — | US | claimed |
| US-20030134830-A1 | Bioavailable prodrugs of androgenic steroids and related method | BIOTEST LABORATORIES, LLC | 2003-07-17 | — | — | US | claimed |
| US-4447424-A | ANTIFERTILITY, ANTIINFLAMMATORY AGENT, HORMONE INHIBITOR | ROUSSEL UCLAF (FR) | 1984-05-08 | — | — | US | claimed |
| US-20050113354-A1 | Bioavailable prodrugs of androgenic steroids and related method | ROBERTS WILLIAM J (US) | 2005-05-26 | — | — | US | disclosed |
| US-6740646-B2 | Bioavailable prodrugs of androgenic steroids and related method | BIOTEST LABORATORIES, LLC | 2004-05-25 | — | — | US | disclosed |
| US-20030134830-A1 | Bioavailable prodrugs of androgenic steroids and related method | BIOTEST LABORATORIES, LLC | 2003-07-17 | — | — | US | disclosed |
| US-20030134831-A1 | Bioavailable prodrugs of androgenic steroids and related method | BIOTEST LABORATORIES, LLC | 2003-07-17 | — | — | US | disclosed |
| US-5182381-A | Intermediates for 3-keto-19-nor-Δ4,9 -steroids | ROUSSEL ULCAF (FR) | 1993-01-26 | — | — | US | disclosed |