Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13415930 | 0.89 | CYP17A1 (0.52) | LMNAMAPTALDH1A1MCL1CYP1A2 | |
| SCHEMBL6436205 | 0.89 | MAPT (0.49) | LMNAMAPTALDH1A1MCL1CYP1A2 | |
| SCHEMBL6442618 | 0.84 | MAPT (0.44) | LMNAMAPTALDH1A1MCL1CYP1A2 | |
| SCHEMBL6442919 | 0.84 | MAPT (0.44) | LMNAMAPTALDH1A1MCL1CYP1A2 | |
| SCHEMBL24103254 | 0.82 | MAPT (0.69) | LMNAMAPTALDH1A1MCL1CYP1A2 | |
| SCHEMBL6445859 | 0.82 | MAPT (0.69) | LMNAMAPTALDH1A1MCL1CYP1A2 | |
| SCHEMBL6437488 | 0.79 | SHBG (0.62) | LMNAMAPTALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL5550721 | 0.79 | MAPT (0.54) | LMNAMAPTALDH1A1MCL1CYP1A2 | |
| SCHEMBL5550789 | 0.78 | MAPT (0.53) | LMNAMAPTALDH1A1MCL1CYP1A2 | |
| SCHEMBL6441434 | 0.77 | MAPT (0.51) | LMNAMAPTALDH1A1MCL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050159366-A1 | Pharmaceutical compositions and treatment methods - 8 | BIOVIE INC. | 2005-07-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159366-A1 | Pharmaceutical compositions and treatment methods - 8 | HSD17B7, NR5A1, HSD3B1 | LMNA 4071/4885MAPT 2579/4885ALDH1A1 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.