Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.54 |
| ▸ | SHBG | P04278 | 5/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.52 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.52 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | G6PD | P11413 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448612 | 1.00 | ESR1 (0.54) | ESR1SHBGESR2SERPINA6SLC22A1 | |
| SCHEMBL6450159 | 1.00 | ESR1 (0.54) | ESR1SHBGESR2SERPINA6SLC22A1 | |
| SCHEMBL6437488 | 0.81 | SHBG (0.62) | ESR1SHBGESR2SERPINA6SLC22A1 | |
| SCHEMBL6442618 | 0.80 | MAPT (0.44) | ESR1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6442919 | 0.80 | MAPT (0.44) | ESR1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6448963 | 0.75 | SHBG (0.65) | ESR1SHBGESR2SERPINA6SLC22A1 | |
| SCHEMBL6575174 | 0.75 | SHBG (0.65) | ESR1SHBGESR2SERPINA6SLC22A1 | |
| SCHEMBL21807739 | 0.75 | SHBG (0.65) | ESR1SHBGESR2SERPINA6SLC22A1 | |
| SCHEMBL547771 | 0.75 | SHBG (0.65) | ESR1SHBGESR2SERPINA6SLC22A1 | |
| SCHEMBL6575143 | 0.75 | SHBG (0.65) | ESR1SHBGESR2SERPINA6SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050282732-A1 | Pharmaceutical compositions and treatment methods-7 | BIOVIE INC. | 2005-12-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282732-A1 | Pharmaceutical compositions and treatment methods-7 | HSD17B7, IL17A, HSD3B1 | ESR1 477/4885SHBG 52/4885ESR2 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.