Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.39 |
| ▸ | NOS2 | P35228 | 4/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440460 | 1.00 | NOS1 (0.39) | NOS1NOS2NOS3KMT2ACA1 | |
| SCHEMBL23352118 | 1.00 | NOS1 (0.39) | NOS1NOS2NOS3KMT2ACA1 | |
| SCHEMBL7179688 | 0.94 | NOS1 (0.36) | NOS1NOS2NOS3 | |
| SCHEMBL11836757 | 0.85 | NOS1 (0.40) | NOS1NOS2NOS3KMT2ACA1 | |
| SCHEMBL6441618 | 0.81 | — | — | |
| SCHEMBL19863566 | 0.81 | — | — | |
| SCHEMBL14539079 | 0.81 | — | — | |
| SCHEMBL6441564 | 0.81 | — | — | |
| SCHEMBL4548488 | 0.81 | NOS1 (0.36) | NOS1NOS2NOS3KMT2ACA1 | |
| SCHEMBL6440814 | 0.79 | NOS1 (0.39) | NOS1NOS2NOS3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215816-A1 | Cyclic ketones, their preparation and their use in the synthesis of amino acids | BLAKEMORE DAVID C | 2005-09-29 | — | — | US | claimed |
| US-6872856-B2 | Cyclic ketones, their preparation and their use in the synthesis of amino acids | WARNER-LAMBERT COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| US-20030187296-A1 | Cyclic ketones, their preparation and their use in the synthesis of amino acids | WARNER-LAMBERT COMPANY | 2003-10-02 | — | — | US | claimed |
| EP-1296921-A1 | CYCLIC KETONES, THEIR PREPARATION AND THEIR USE IN THE SYNTHESIS OF AMINO ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-02 | — | — | EP | claimed |
| WO-2002000584-A1 | CYCLIC KETONES, THEIR PREPARATION AND THEIR USE IN THE SYNTHESIS OF AMINO ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-03 | — | — | WO | claimed |
| US-20050215816-A1 | Cyclic ketones, their preparation and their use in the synthesis of amino acids | BLAKEMORE DAVID C | 2005-09-29 | — | — | US | disclosed |
| US-6872856-B2 | Cyclic ketones, their preparation and their use in the synthesis of amino acids | WARNER-LAMBERT COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| US-20030187296-A1 | Cyclic ketones, their preparation and their use in the synthesis of amino acids | WARNER-LAMBERT COMPANY | 2003-10-02 | — | — | US | disclosed |
| EP-1296921-A1 | CYCLIC KETONES, THEIR PREPARATION AND THEIR USE IN THE SYNTHESIS OF AMINO ACIDS | WARNER-LAMBERT COMPANY (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002000584-A1 | CYCLIC KETONES, THEIR PREPARATION AND THEIR USE IN THE SYNTHESIS OF AMINO ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215816-A1 | Cyclic ketones, their preparation and their use in the synthesis of amino acids | BCAT1, BCAT2, AKR1C3 | NOS1 1273/4885NOS2 2081/4885NOS3 1337/4885 |
| US-20030187296-A1 | Cyclic ketones, their preparation and their use in the synthesis of amino acids | BCKDK, GABRR1, GAP43 | NOS1 3579/4885NOS2 4224/4885NOS3 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.