SCHEMBL6438829

SCHEMBL6438829

Cc1ccc(O)c(P(c2cc(C)ccc2O)c2cc(C)ccc2O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.56
ALOX15 P16050 3/20 0.56
HSD17B10 Q99714 2/20 0.56
ALDH1A1 P00352 1/20 0.56
TP53 P04637 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
LMNA P02545 4/20 0.54
MAPT P10636 3/20 0.54
MEN1 O00255 1/20 0.54
GAA P10253 1/20 0.54
HPGD P15428 1/20 0.54
ALOX12 P18054 1/20 0.54
KMT2A Q03164 1/20 0.54
CSNK2A1 P68400 1/20 0.45
AMY1A P0DUB6 1/20 0.42
CHRM1 P11229 1/20 0.41
SLC6A2 P23975 1/20 0.41
ADRA1A P35348 1/20 0.41
HTR2B P41595 1/20 0.41
NPC1 O15118 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7189644 0.83 ALOX15 (0.45) TRPA1ALOX15HSD17B10ALDH1A1TP53
SCHEMBL5596542 0.83 ALOX15 (0.45) TRPA1ALOX15HSD17B10ALDH1A1TP53
SCHEMBL5596101 0.83 TP53 (0.54) TRPA1ALOX15HSD17B10ALDH1A1TP53
SCHEMBL5596910 0.83 TRPA1 (0.54) TRPA1ALOX15HSD17B10ALDH1A1TP53
SCHEMBL5596401 0.79 TRPA1 (0.50) TRPA1ALOX15HSD17B10ALDH1A1TP53
SCHEMBL5596924 0.79 ALOX15 (0.45) TRPA1ALOX15HSD17B10ALDH1A1TP53
SCHEMBL5596679 0.78 TRPA1 (0.48) TRPA1ALOX15HSD17B10ALDH1A1TP53
SCHEMBL5596851 0.78 TRPA1 (0.48) TRPA1ALOX15HSD17B10ALDH1A1TP53
SCHEMBL5596168 0.78 TRPA1 (0.48) TRPA1ALOX15HSD17B10ALDH1A1TP53
SCHEMBL5596568 0.76 ESR2 (0.42) TRPA1ALOX15HSD17B10ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1268665-B1 FLAME RETARDANT PHOSPHORUS ELEMENT-CONTAINING EPOXY RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC (US) 2005-11-02 EP claimed