Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596542 | 0.96 | ALOX15 (0.45) | ALOX15HSD17B10ALDH1A1TRPA1LMNA | |
| SCHEMBL6438829 | 0.83 | TRPA1 (0.56) | ALOX15HSD17B10ALDH1A1TRPA1LMNA | |
| SCHEMBL15723539 | 0.82 | TDP1 (0.46) | ALDH1A1LMNAGAAHPGDALOX12 | |
| SCHEMBL3679308 | 0.80 | ESR2 (0.56) | ALOX15HSD17B10ALDH1A1LMNAMEN1 | |
| SCHEMBL12592439 | 0.80 | TDP1 (0.44) | ALDH1A1LMNAMEN1GAAKMT2A | |
| SCHEMBL25176323 | 0.80 | ESR2 (0.56) | ALOX15HSD17B10ALDH1A1LMNAMEN1 | |
| SCHEMBL29543525 | 0.80 | ESR2 (0.56) | ALOX15HSD17B10ALDH1A1LMNAMEN1 | |
| SCHEMBL9909848 | 0.79 | TDP1 (0.52) | ALOX15HSD17B10ALDH1A1LMNAMEN1 | |
| SCHEMBL7187736 | 0.79 | TRPA1 (0.39) | ALOX15HSD17B10ALDH1A1TRPA1LMNA | |
| SCHEMBL7193988 | 0.79 | TRPA1 (0.39) | ALOX15HSD17B10ALDH1A1TRPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130005972-A1 | Application of Staudinger Ligation in PET Imaging | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2013-01-03 | — | — | US | disclosed |
| WO-2011123444-A1 | APPLICATION OF STAUDINGER LIGATION IN PET IMAGING | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
| US-6559326-B1 | Substituted phosphinophenoxide-metal complexes for the polymerization of olefins | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-06 | — | — | US | disclosed |
| EP-1101768-B1 | Substituted Phosphanylphenolato[P,O]-metal-complexes for Polymerisation of Olefines | BASF AG (DE) | 2002-10-02 | — | — | EP | disclosed |
| EP-1101768-A1 | Substituted Phosphanylphenolato[P,O]-metal-complexes for Polymerisation of Olefines | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005972-A1 | Application of Staudinger Ligation in PET Imaging | SSTR4, TIE1, STAU1 | ALOX15 2545/4885HSD17B10 3696/4885ALDH1A1 1018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.