Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61038 | 0.79 | CYP3A4 (0.50) | ALDH1A1CYP3A4LMNAHCAR2HPGD | |
| SCHEMBL6435517 | 0.76 | CYP2C19 (0.42) | ALDH1A1CYP3A4HCAR2TRPA1CYP2C19 | |
| SCHEMBL299791 | 0.75 | HPGD (0.42) | ALDH1A1CYP3A4LMNAHCAR2HPGD | |
| SCHEMBL9472147 | 0.75 | CYP3A4 (0.46) | ALDH1A1CYP3A4LMNAHCAR2HPGD | |
| SCHEMBL2886386 | 0.74 | CYP2C19 (0.43) | ALDH1A1CYP3A4LMNAHCAR2HPGD | |
| SCHEMBL2886387 | 0.74 | CYP2C19 (0.43) | ALDH1A1CYP3A4LMNAHCAR2HPGD | |
| SCHEMBL5837445 | 0.74 | KMT2A (0.47) | ALDH1A1CYP3A4LMNAHCAR2HPGD | |
| SCHEMBL6434417 | 0.73 | CYP2C19 (0.34) | ALDH1A1TRPA1CYP2C19 | |
| SCHEMBL14011311 | 0.72 | HCAR2 (0.42) | ALDH1A1CYP3A4LMNAHCAR2HPGD | |
| SCHEMBL7948698 | 0.72 | CYP3A4 (0.44) | ALDH1A1CYP3A4LMNAHCAR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867323-B2 | Cross-coupling reaction of organosilicon nucleophiles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-03-15 | — | — | US | disclosed |
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | TST, HPD, PCNA | ALDH1A1 2157/4885CYP3A4 1247/4885LMNA 4232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.