Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61038 | 0.95 | CYP3A4 (0.50) | CYP3A4ALDH1A1HPGDHCAR2LMNA | |
| SCHEMBL7948698 | 0.87 | CYP3A4 (0.44) | CYP3A4ALDH1A1HPGDHCAR2LMNA | |
| SCHEMBL9642843 | 0.85 | PTGS2 (0.46) | CYP3A4ALDH1A1CYP2C19MAPTPTGS1 | |
| SCHEMBL8947205 | 0.81 | LMNA (0.46) | CYP3A4ALDH1A1LMNATSHR | |
| SCHEMBL29034776 | 0.81 | TPMT (0.35) | CYP3A4ALDH1A1TSHRKDM4EMAPT | |
| SCHEMBL27628648 | 0.81 | CYP1A2 (0.44) | CYP3A4ALDH1A1LMNATSHRCYP2C19 | |
| SCHEMBL27082345 | 0.81 | HPGD (0.43) | CYP3A4ALDH1A1HPGDHCAR2LMNA | |
| SCHEMBL2886387 | 0.80 | CYP2C19 (0.43) | CYP3A4ALDH1A1HPGDHCAR2LMNA | |
| SCHEMBL2886386 | 0.80 | CYP2C19 (0.43) | CYP3A4ALDH1A1HPGDHCAR2LMNA | |
| SCHEMBL299791 | 0.80 | HPGD (0.42) | CYP3A4ALDH1A1HPGDHCAR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262297-A | Medical diagnosis with active materials bound to polymers | EASTMAN KODAK COMPANY (US) | 1993-11-16 | — | — | US | disclosed |