Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL30661306 | 0.89 | ACHE (0.51) | ACHECA12CA1CA2CA7 | |
| SCHEMBL19681458 | 0.85 | CA1 (0.48) | CA12CA1CA2CA7CA9 | |
| Trifluoromethanesulfonic Acid SCHEMBL6441504 | 0.78 | POLB (0.40) | ACHECA12CA1CA2CA7 | |
| Trifluoromethanesulfonic Acid SCHEMBL29657173 | 0.74 | ACHE (0.40) | ACHEKCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL20495605 | 0.74 | ACHE (0.40) | ACHEKCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL9686740 | 0.71 | KCNH2 (0.44) | ACHEKCNH2GPR3 | |
| Trifluoromethanesulfonic Acid SCHEMBL16346643 | 0.70 | ACHE (0.55) | ACHEKCNH2GPR3 | |
| SCHEMBL29867407 | 0.70 | ACKR3 (0.39) | ACHECA12CA1CA2CA7 | |
| SCHEMBL21200030 | 0.70 | ACKR3 (0.39) | ACHECA12CA1CA2CA7 | |
| Trifluoromethanesulfonic Acid SCHEMBL2996949 | 0.70 | ACHE (0.42) | ACHECA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201627-B1 | Ring fluorination of non-activated aromatic compounds | AIR PROD & CHEM (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1201628-B1 | Electrophilic fluorination | AIR PROD & CHEM (US) | 2005-12-14 | — | — | EP | disclosed |
| US-6737525-B2 | USEFUL IN FLUORINATING, PREFERABLY IN A NITROMETHANE SOLVENT, CARBANIONIC SPECIES AND/OR ACTIVATED AROMATIC COMPOUNDS | AIR PRODUCTS AND CHEMICALS, INC. | 2004-05-18 | — | — | US | disclosed |
| US-6635760-B2 | Fluorinating a substrate selected from unsubstituted aromatic compounds and aromatic compounds having electron withdrawing substituent(s) comprises contacting substrate with a tri(halo or trifluoromethyl) substituted N-fluorotriazinium salt | AIR PRODUCTS AND CHEMICALS, INC. | 2003-10-21 | — | — | US | disclosed |
| US-20020123657-A1 | Electrophilic fluorination | AIR PRODUCTS AND CHEMICALS, INC. | 2002-09-05 | — | — | US | disclosed |
| US-20020055662-A1 | Ring fluorination of non-activated aromatic compounds | AIR PRODUCTS AND CHEMICALS, INC. | 2002-05-09 | — | — | US | disclosed |
| EP-1201627-A1 | Ring fluorination of non-activated aromatic compounds | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-05-02 | — | — | EP | disclosed |
| EP-1201628-A1 | Electrophilic fluorination | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123657-A1 | Electrophilic fluorination | PFAS, SRC, SFN | ACHE 3260/4885CA12 1636/4885CA1 523/4885 |
| US-20020055662-A1 | Ring fluorination of non-activated aromatic compounds | NAF1, NPM1, AFF1 | ACHE 2997/4885CA12 1836/4885CA1 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.