Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL6441504

COC(=O)c1ccc(C(=O)OC)[n+](F)c1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.40

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
CA1 P00915 4/20 0.40
CA2 P00918 4/20 0.40
CA12 O43570 3/20 0.40
CA9 Q16790 3/20 0.40
CA14 Q9ULX7 3/20 0.40
NOTUM Q6P988 2/20 0.38
FBP1 P09467 1/20 0.38
VCAM1 P19320 1/20 0.38
STS P08842 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA7 P43166 1/20 0.38
HPGD P15428 2/20 0.37
GLA P06280 1/20 0.37
CYP2C9 P11712 1/20 0.36
RAB9A P51151 1/20 0.36
ALDH1A1 P00352 1/20 0.36
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL6439196 0.78 ACHE (0.43) CA1CA2CA12CA9CA14
Trifluoromethanesulfonic Acid SCHEMBL30661306 0.76 ACHE (0.51) CA1CA2CA12CA9CA14
Trifluoromethanesulfonic Acid SCHEMBL29839711 0.75 CA1 (0.46) POLBCA1CA2CA12CA9
Trifluoromethanesulfonic Acid SCHEMBL17554584 0.74 CA1 (0.45) POLBCA1CA2CA12CA9
SCHEMBL1615851 0.72 CA1 (0.47) POLBCA1CA2CA12CA9
SCHEMBL29550577 0.72 CA1 (0.47) POLBCA1CA2CA12CA9
Trifluoromethanesulfonic Acid SCHEMBL31221600 0.70 LOXL2 (0.46) POLBCA1CA2CA12CA9
Trifluoromethanesulfonic Acid SCHEMBL406729 0.70 TSHR (0.49) POLBCA1CA2CA12CA9
Trifluoromethanesulfonic Acid SCHEMBL20495605 0.70 ACHE (0.40) POLBALDH1A1ACHE
Trifluoromethanesulfonic Acid SCHEMBL29657173 0.70 ACHE (0.40) POLBALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1201627-B1 Ring fluorination of non-activated aromatic compounds AIR PROD & CHEM (US) 2005-12-14 EP disclosed