⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1060208 | 0.65 | — | — | |
| SCHEMBL6140059 | 0.64 | ALDH1A1 (0.35) | — | |
| SCHEMBL9046563 | 0.64 | — | — | |
| SCHEMBL11117982 | 0.62 | — | — | |
| SCHEMBL6754000 | 0.60 | — | — | |
| SCHEMBL6754004 | 0.60 | — | — | |
| SCHEMBL5446574 | 0.60 | — | — | |
| SCHEMBL7157029 | 0.60 | — | — | |
| SCHEMBL28731096 | 0.60 | LMNA (0.40) | — | |
| SCHEMBL2011304 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1152009-B2 | NOVEL NUCLEOSIDES AND OLIGONUCLEOTIDE ANALOGUES | DAIICHI SANKYO CO LTD (JP) | 2017-09-06 | — | — | EP | disclosed |
| EP-1152009-B1 | NOVEL NUCLEOSIDES AND OLIGONUCLEOTIDE ANALOGUES | SANKYO CO (JP) | 2005-01-26 | — | — | EP | disclosed |