Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGAV | P06756 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.38 |
| ▸ | DRD3 | P35462 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439601 | 0.80 | ITGB3 (0.54) | ITGB3ITGAVLMNASMN1; SMN2 | |
| SCHEMBL6440635 | 0.78 | ITGB3 (0.55) | ITGB3ITGAV | |
| SCHEMBL5026370 | 0.78 | ITGB3 (0.63) | ITGB3ITGAV | |
| SCHEMBL6447753 | 0.71 | WDR5 (0.41) | ITGB3ITGAVLMNA | |
| SCHEMBL6424193 | 0.70 | ITGB3 (0.59) | ITGB3ITGAV | |
| SCHEMBL6445537 | 0.70 | ITGB3 (0.49) | ITGB3ITGAVLMNASMN1; SMN2 | |
| SCHEMBL31035870 | 0.70 | ALOX12 (0.58) | ITGB3ITGAVALOX12GAAHTT | |
| SCHEMBL6440900 | 0.69 | ITGB3 (0.49) | ITGB3ITGAV | |
| SCHEMBL6439156 | 0.69 | LMNA (0.51) | LMNASMN1; SMN2 | |
| SCHEMBL5879524 | 0.66 | ITGB3 (1.00) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |